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WRW4
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WRW4

CAS: 878557-55-2

Ref. 01-H-7596

1mg
67.00 €Add to cart
Estimated delivery in United States, on Tuesday 14 Dec 2021

Product Information

Name:
WRW4
Description:
Antagonist of formyl peptide receptor-like 1 (FPRL1) signalling. WRW4 inhibits WKYMVm binding to FPRL1 (IC50 0.23 mM) as well as the intracellular calcium release induced by WKYMVm, MMK-1, amyloid b42, and F peptide. The tryptophan-rich peptide also inhibits FPRL1-mediated signalling in human neutrophils and blocks chemotactic migration and superoxide generation by Ab42. WRW4 inhibited the activation of FPRL2 by F2L, an FPRL2-selective endogenous agonist, resulting in the complete inhibition of intracellular calcium increase and chemotactic migration.
Long term storage:
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Chemical properties

Molecular weight:
1103.52422
Formula:
C61H65N15O6
Purity:
95.0%
Color/Form:
White Lyophilisate
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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