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Mca-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide
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Mca-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide

CAS: 438625-61-7

Ref. 01-M-2465

1mg
411.00 €Add to cart
5mg
1,501.00 €Add to cart
Estimated delivery in United States, on Monday 13 Dec 2021

Product Information

Name:
Mca-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide
Synonyms:
  • Mca-(Asn670,Leu671)-APP770 (667-676)-Lys(Dnp)-Arg-Arg amide
  • L-Argininamide,N-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-seryl-L-a-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-a-aspartyl-L-alanyl-L-a-glutamyl-L-phenylalanyl-L-arginyl-N6-(2,4-dinitrophenyl)-L-lysyl-L-arginyl-(9CI)
Description:
This fluorescent (FRET) peptide substrate contains the 'Swedish' Lys-Met/Asn-Leu mutation of the amyloid precursor protein (APP) b-secretase cleavage site. Mca-SEVNLDAEFRK(Dnp)RR-amide has been used for assaying b-secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). The results suggested that TOP is a potential b-secretase candidate and is involved in the processing of APP in vivo.
Long term storage:
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Chemical properties

Molecular weight:
1999.91365
Formula:
C86H125N27O29
Purity:
93.8%
Color/Form:
Yellow Powder
MDL:
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Hazard Info

UN Number:
EQ:
Class:
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Forbidden to fly:
Hazard Info:
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LQ:

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