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Abz-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (669-674)-EDDnp
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Abz-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (669-674)-EDDnp

CAS: 1007306-20-8

Ref. 01-M-2565

1mg
127.00 €Add to cart
5mg
476.00 €Add to cart
Estimated delivery in United States, on Monday 13 Dec 2021

Product Information

Name:
Abz-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (669-674)-EDDnp
Synonyms:
  • JMV2236, Abz-(Asn670,Leu671)-APP770 (669-674)-EDDnp
Description:
Intramolecularly quenched fluorescent substrate containing the ortho-aminobenzoyl (Abz) / N-(2,4-dinitrophenyl)ethylenediamine (EDDnp) groups as the donor / acceptor pair. It corresponds to the Swedish-mutated (JMV2236) b-amyloid precursor protein (bAPP) sequence targeted by b-secretase BACE (b-site APP-cleaving activity). This FRET substrate is more selectively cleaved by BACE1 and BACE2 than by cathepsin D, a disintegrin and metalloprotease 10 (ADAM10), tumor necrosis a-converting enzyme (TACE), presenilin-1 (PS1), or presenilin-2 (PS2).
Long term storage:
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Chemical properties

Molecular weight:
986.40937
Formula:
C42H58N12O16
Purity:
98.2%
MDL:
Melting point:
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Concentration:
EINECS:
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Hazard Info

UN Number:
EQ:
Class:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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