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L-trans-Epoxysuccinyl(propylamide)-Ile-Pro-OMe, CA-074Me, N-(L-3-trans-(Propylamino)carbonyl)-oxirane-2-carbonyl)-Ile-Pro-OMe

CAS: 147859-80-1

Ref. 01-N-1660

1mg
143.00 €Add to cart
5mg
548.00 €Add to cart
Estimated delivery in United States, on Tuesday 7 Dec 2021

Product Information

Name:
L-trans-Epoxysuccinyl(propylamide)-Ile-Pro-OMe, CA-074Me, N-(L-3-trans-(Propylamino)carbonyl)-oxirane-2-carbonyl)-Ile-Pro-OMe
Synonyms:
  • L-Trans-Epoxysuccinyl-Ile-Pro-Ome Propylamide
  • L-Trans-Epoxysuccinyl (Propylamide)-Ile-Pro-Ome
  • Cathepsin B Inhibitor Iv
  • [L-3-Trans-(Polycarbamoyl)Oxirane-2-Carbonyl]-L-Isoleucyl-L-Proline Methyl Ester
  • (L-3-Trans-(Propylcarbamoyl)Oxirane-2-Carbonyl)-L-Isoleucyl-L-Proline Methyl Ester
  • [L-3-Trans-(Propylcarbamoyl)Oxyrane-2-Carbonyl]-L-Isoleucyl-L-Proline Methyl Ester
  • N-((L-3-Trans-(Propylamino)Carbonyl)-Oxirane-2-Carbonyl)-Ile-Pro-Ome
Description:
CA-074Me, the membrane-permeant prodrug of CA-074, represents a proinhibitor, that itself is almost inactive, but can enter cells and there inhibit intracellular cathepsin B. Therefore CA-074Me is suggested to be a very promising reagent for the investigation of the intracellular functions of cathepsin B. This cysteine protease showing b-secretase activity could be involved in amyloid b formation.
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Chemical properties

Molecular weight:
397.22129
Formula:
C19H31N3O6
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Hazard Info

UN Number:
EQ:
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Forbidden to fly:
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Technical inquiry about: 01-N-1660 L-trans-Epoxysuccinyl(propylamide)-Ile-Pro-OMe, CA-074Me, N-(L-3-trans-(Propylamino)carbonyl)-oxirane-2-carbonyl)-Ile-Pro-OMe

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