Product Information
- diethyl cyanomethylphosphonate
- (Cianometil)Fosfonato De Dietilo
- (Cyanomethyl)Phosphonate De Diethyle
- (Cyanomethyl)diethoxyphosphine oxide
- (Diethoxyphosphinyl)acetonitrile
- (Diethoxyphosphono)acetonitrile
- (Diethylphosphono)acetonitrile
- 2-(Diethylphosphonyl)acetonitrile
- 2-Diethoxyphosphorylacetonitrile
- Cyanomethanephosphonic acid, diethyl ester
- See more synonyms
- Cyanomethyl phosphonic acid diethyl ester
- Cyanomethylphosphonic acid diethyl ester~Diethyl phosphonoacetonitrile
- Diethyl (Cyanomethyl)Phosphonate
- Diethyl P-(cyanomethyl)phosphonate
- Diethyl cyanomethanephosphonate
- Diethyl cyanomethylphosphonoacetate
- Diethyl-(cyanomethyl)phosphonat
- Diethylphosphonoacetonitrile
- Nsc 407826
- O,O-Diethyl (cyanomethyl)phosphonate
- Phosphonic acid, (cyanomethyl)-, diethyl ester
- Phosphonic acid, P-(cyanomethyl)-, diethyl ester
Diethyl cyanomethyl phosphonate is used as an intermediate in Horner-Emmons reaction for the synthesis of substituted nitriles and their amide and heterocyclic derivatives. It is known as a modified Wittig reagent used in the preparation of alpha, beta-unsaturated nitriles from ketones or aldehydes like 3-hydroxy-3-methylbutanal. It reacts with epoxides and nitrones to prepare cyano-substituted cyclopropanes and aziridines respectively. It is actively involved in the synthesis of alpha-arylated alkanenitriles via reaction with aryl iodides in presence of CuI. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Chemical properties
Technical inquiry about: 02-A10218 Diethyl cyanomethylphosphonate, 96%
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