Phorbol 12-myristate 13-acetate, >94%

CAS: 16561-29-8

Ref. 02-J63916

Product Information

• Name: Phorbol 12-myristate 13-acetate, >94%
• Synonyms: phorbol ester tpa (phorbol derivative) tpa (tetradecanoylphorbol acetate) PMA tetradecanoylphorbol acetate, 4a α isomer factor A1 4a α isomer tetradecanoylphorbol acetate myristate acetate, phorbol acetate, tetradecanoylphorbol phorbol-myristate acetate, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl tetradecanoate, 1,6,8-Beta-Tetramethyl-L)-9A-Acetate9-Myristate, 12-O-Tetradecanoylphorbol 13-acetate, 12-O-Tetradecanoylphorbolacetate, 12-O-Tetradekanoylphorbol-13-Acetat, 12-Tetradecanoylphorbol 13-acetate, 12-Tetradecanoylphorbol 13-monoacetate, 12-Tetradecanoylphorbol13-Monoacetate, 13-O-Acetylphorbol 12-myristate, 1H-Cyclopropa[3,4]benz[1,2-e]azulene, tetradecanoic acid deriv., 4β-Phorbol 12-myristate 13-acetate, Factor A1, Factor A1 (croton oil), Factor A₁, Factor A₁ (croton oil), Myristic acid, 9-ester with 1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-decahydro-4aβ,7bα,9β,9aα-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one 9a-acetate, (+)-, Nsc 262244, PMA, PMA (tumor promoter), Pd 616, Phorbol 12-tetradecanoate 13-acetate, Phorbol myristate acetate, TPA, TPA (phorbol derivative), Tetradecanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester, Tetradecanoic acid, 9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester, [1aR-(1aα,1bβ,4aβ,7aα,7bα,8α,9β,9aα)]-, Tetradecanoylphorbol acetate, β-Phorbol 12-myristate 13-acetate

Description

PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 616.84
• Formula: C₃₆H₅₆O₈
• Purity: 94%
• Color/Form: White to pale cream, Powder, film or foam, solid
• InChI key: PHEDXBVPIONUQT-RGYGYFBISA-N