10-538244 - r-tert-butyl-1-2-chlorophenyl-2-oxocyclohexylcarbamate

4-N-Cbz-aminocyclohexanone

<p>4-Aminocyclohexan-1-one, N-BOC protected</p>

<p>Applications 4-(N-Boc-amino)cyclohexanone is an intermediate in the synthesis of tert-Butyl 1,7-diazaspiro[3.5]nonane-1-carboxylate (B692795). tert-Butyl 1,7-diazaspiro[3.5]nonane-1-carboxylate is a reagent in the preparation of -[4-fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazin-3(2H)-ones as a potent poly(ADP-ribose) polymerase-1 inhibitors active in BRCA deficient cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ferrigno, F., et al.: Bioorg. Med. Chem. Lett., 20, 1100 (2010);<br></p>

<p>4-N-Boc-aminocyclohexanone is a chemical that inhibits the proliferation of cancer cells in vitro. It also has an antiproliferative effect on fibroblast cells, which may be due to its ability to inhibit protein synthesis and induce cell death by apoptosis. 4-N-Boc-aminocyclohexanone can also be used for the preparation of photoresponsive polymers that are used in drug delivery systems. This compound can be prepared by reacting 4-aminocyclohexanol with formaldehyde in the presence of base. This reaction forms a five-membered ring via an amide bond. The amide group is then hydrolyzed to form the corresponding carboxylic acid. The colorimetric method is used to determine the degree of hydrolysis, which is determined by measuring the absorbance at 590 nm. In addition, this compound can be used as a reactive intermediate for other compounds like</p>

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3-N-Boc-aminocyclohexanone is a potent inhibitor of gram-positive and gram-negative bacteria, including the class of pyrazoles. It is a linker that binds to the topoisomerase II enzyme and inhibits DNA synthesis by preventing the formation of the topoisomerase II/DNA complex. 3-N-Boc-aminocyclohexanone also has antibacterial activity against gram-positive bacteria, inhibiting their growth by binding to the protein synthesis machinery. 3-N-Boc-aminocyclohexanone has shown antimicrobial properties against bacterial strains that are resistant to other antibiotics such as penicillin and erythromycin.