2,4-Diacetylphloroglucinol

CAS: 2161-86-6

Ref. 3D-AD21440

Product Information

• Name: 2,4-Diacetylphloroglucinol
• Synonyms: 1,1'-(2,4,6-Trihydroxy-1,3-phenylene)bis-ethanone1,3-Diacetyl-2,4,6-trihydroxybenzene5-Acetyl-2,4,6-trihydroxyacetophenone, 1,1'-(2,4,6-Trihydroxy-1,3-phenylene)bisethanone, 1,1'-(2,4,6-Trihydroxybenzene-1,3-Diyl)Diethanone, 1,1′-(2,4,6-Trihydroxy-1,3-phenylene)bis[ethanone], 1,3-Diacetyl-2,4,6-trihydroxybenzene, 1-(3-Acetyl-2,4,6-trihydroxyphenyl)ethan-1-one, 1-(3-Acetyl-2,4,6-trihydroxyphenyl)ethanone, 2,4,6-Trihydroxy-1,3-diacetylbenzene, 2,4-Diacetyl-1,3,5-benzenetriol, 5-Acetyl-2,4,6-trihydroxyacetophenone, Brn 1881572, Ethanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis- (9CI), Ethanone, 1,1′-(2,4,6-trihydroxy-1,3-phenylene)bis-, Ipo 15474Fs, K-2, K₂, K₂ (pharmaceutical), Phloroglucinol, diacetyl-

Description

2,4-Diacetylphloroglucinol is a chemical compound that belongs to the group of 2,4-diacetylphloroglucinols. It is a structural analog of p-hydroxybenzoic acid and can be synthesized by reacting acetylchloride with phloroglucinol in the presence of sodium hydroxide. 2,4-Diacetylphloroglucinol has been shown to inhibit bacterial growth through an intramolecular hydrogen bond. This inhibition may be due to its ability to act as a receptor for bacterial RNA polymerase, thereby inhibiting transcription and replication. 2,4-Diacetylphloroglucinol has also been shown to have mitochondrial membrane potential activity in a model system of nutrient solution containing hydrogen peroxide.
2,4-Diacetylphloroglucinol inhibits wild type strains of bacteria such as Escherichia coli

• Brand: Biosynth

Chemical properties

• Molecular weight: 210.18 g/mol
• Formula: C₁₀H₁₀O₅
• Purity: Min. 95%
• Color/Form: Beige Powder
• InChI: InChI=1S/C10H10O5/c1-4(11)8-6(13)3-7(14)9(5(2)12)10(8)15/h3,13-15H,1-2H3
• InChI key: InChIKey=PIFFQYJYNWXNGE-UHFFFAOYSA-N
• SMILES: CC(=O)c1c(O)cc(O)c(C(C)=O)c1O