(2E)-1-(1,5-Dimethyl-1H-pyrazol-4-yl)-3-(dimethylamino)prop-2-en-1-one
CAS: 1001500-19-1
Ref. 3D-BQB50019
1g | Discontinued | ||
10mg | Discontinued | ||
50mg | Discontinued | ||
100mg | Discontinued | ||
250mg | Discontinued | ||
500mg | Discontinued |
Product Information
(2E)-1-(1,5-Dimethyl-1H-pyrazol-4-yl)-3-(dimethylamino)prop-2-en-1-one is a nonsteroidal anti-inflammatory drug that belongs to the group of p2 inhibitors. It has been shown to inhibit COX 2 and IL 1β with significant cytotoxicity in mouse tumor models. This compound also inhibits the production of proinflammatory cytokines IL 10 and TNFα. (2E)-1-(1,5-Dimethyl-1H-pyrazol-4-yl)-3-(dimethylamino)prop-2 -en 1 one is an active analogue of indomethacin. In addition, it has been reported to have inhibitory properties against MMP9 activity in vitro.