Product Information
NSC59984 is an anti-cancer drug that has been shown to inhibit the proliferation of cancer cells and induce apoptosis in vitro. It is an inhibitor of ubiquitin ligases, which are enzymes that regulate the proteasomal degradation pathway by targeting specific proteins for degradation. NSC59984 has been shown to inhibit the activity of pro-apoptotic protein p21 and p53, which are proteins involved in cell cycle regulation. This drug also inhibits mutant p53, which may be due to its ability to bind to the ubiquitin ligase that targets mutant p53 for degradation.
Chemical properties
Technical inquiry about: 3D-DHB64740 NSC59984
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