Product Information
4-Phenylbenzenesulfonamide (4PBSA) is a phenoxy compound that binds to the active site of histone deacetylase and inhibits its activity. It has been shown that 4PBSA can inhibit acetylation at nanomolar concentrations and it may be an effective treatment for cancer. The effects of 4PBSA were studied in two different assays, one using cisplatin and the other using nitro. Nitro was found to have a more potent effect than cisplatin, but both compounds had similar results in the assays. 4PBSA has also been shown to be an estrogen receptor antagonist, which may explain some of its anticancer properties. This drug may also inhibit DNA replication by binding to human estrogen receptors and preventing transcriptional activation.
Chemical properties
Technical inquiry about: 3D-EAA37123 4-Phenylbenzene-1-sulfonamide
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