Product Information
5-Bromo-7-methyl-1H-1,2,3-benzotriazole is a potent inhibitor of the protein kinase CK2. It binds to the ATP binding site of CK2 and inhibits its activity by forming a covalent bond with the enzyme. This leads to a reduction in phosphorylation of cellular proteins and decreased cell proliferation. 5-Bromo-7-methyl-1H-1,2,3-benzotriazole has been shown to be effective against benzene exposure in animal models. It also inhibits benzimidazole and benzotriazole, which are important industrial chemicals used for insecticides and fungicides. The substitution of bromine for hydrogen on the benzene ring confers higher potency as an inhibitor.
Chemical properties
Technical inquiry about: 3D-EEC77743 5-Bromo-7-methyl-1H-1,2,3-benzotriazole
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