H-DL-Ala-OEt·HCl
CAS: 17344-99-9
Ref. 3D-FA107888
| 2g | 139.00 € | ||
| 5g | 192.00 € | ||
| 10g | 307.00 € | ||
| 25g | 451.00 € | ||
| 50g | 642.00 € |
Product Information
H-DL-Ala-OEt·HCl (Dabigatran) is a quinolizidine alkaloid that is used in the treatment of patients with atrial fibrillation. It has been shown to inhibit the activity of the enzyme amine oxidase, which converts l-arginine to l-glutamic acid. Dabigatran etexilate, an ester prodrug of dabigatran, is hydrolyzed by esterases in blood plasma to release dabigatran, which then blocks the conversion of l-arginine to l-glutamic acid. This inhibition leads to a decrease in platelet aggregation and thrombin formation and thereby reduces blood clotting. Dabigatran etexilate also binds to primary amines on proteins such as albumin and α1-acid glycoprotein. This binding prevents the binding of other drugs such as warfarin or cl
Chemical properties
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