Amyloid β-Protein (31-35)

CAS: 149385-65-9

Ref. 3D-FA109633

Product Information

• Name: Amyloid β-Protein (31-35)
• Synonyms: ?-Amyloid (31-35)H-Ile-Ile-Gly-Leu-Met-OH
• Brand: Biosynth
• Description: Amyloid beta protein is a peptide that is a major component of the amyloid plaques found in the brain of patients with Alzheimer's disease. Amyloid beta protein (Aβ) has been shown to form fibers and fibrils, which are aggregates of polymerized Aβ peptides. These fibrils can be imaged using a fluorescent dye called dansyl. The dansyl-labeled Aβ fibrils have been shown to have a morphology similar to that seen in electron micrographs of amyloid plaques. The quantum yield for luminescence was found to be 0.1% for the Aβ fibrils but only 0.001% for the monomeric form of Aβ peptides (Aβ 1-40). This suggests that the Aβ peptides are undergoing aggregation into amyloid beta protein fibrils before they can emit light as fluorescence or phosphorescence.

Chemical properties

• Molecular weight: 545.74 g/mol
• Formula: C₂₅H₄₇N₅O₆S
• Purity: Min. 95%