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AYPGKF-NH2 Trifluoroacetate salt
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AYPGKF-NH2 Trifluoroacetate salt

CAS: 352017-71-1

Ref. 3D-FA109702

1mg
257.00 €
2mg
418.00 €
5mg
743.00 €
10mg
1,159.00 €
25mg
2,519.00 €
Estimated delivery in United States, on Wednesday 3 Jul 2024

Product Information

Name:
AYPGKF-NH2 Trifluoroacetate salt
Synonyms:
  • AYPGKF amide PAR-4 Agonist Peptide
Description:

PAR4 is a member of the PAR family of G-protein coupled receptors that are involved in inflammatory responses. PAR4 is activated by leukocyte recruitment, carrageenan, and additives such as fatty acids and fatty acid esters. PAR4 activation leads to neutrophil recruitment and activation. The biological function of PAR4 is to activate neutrophils and platelets, but it also has an important role in inflammation by increasing the production of reactive oxygen species (ROS).
A synthetic small molecule ligand for this receptor has been identified that can act as a potential drug candidate for inflammatory diseases. This compound was found to be a potent inhibitor of ROS production in stimulated human neutrophils, which may be due to its ability to inhibit the release of arachidonic acid from membrane phospholipids.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
680.79 g/mol
Formula:
C34H48N8O7
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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