Ac-Ile-Glu-Thr-Asp-AMC
CAS: 348079-17-4
Ref. 3D-FA110583
| 2mg | 338.00 € | ||
| 5mg | 563.00 € | ||
| 10mg | 933.00 € | ||
| 25mg | 1,756.00 € | ||
| 50mg | 3,053.00 € |
Product Information
- Ac-IETD-AMC
- Caspase-3 Precursor Protease Substrates
Ac-Ile-Glu-Thr-Asp-AMC is a reactive, nonsteroidal anti-inflammatory drug that inhibits the activity of survivin, which is an important protein for the survival of prostate cancer cells. Ac-Ile-Glu-Thr-Asp-AMC also inhibits mitochondrial membrane potential in prostate cancer cells and normal peripheral blood mononuclear cells, leading to apoptosis. The biochemical properties of Ac-Ile-Glu-Thr-Asp-AMC are similar to those of other NSAIDs. This drug has been shown to inhibit protein synthesis in experimental models and hydrochloric acid causes mitochondrial membrane depolarization, which triggers apoptosis.
Chemical properties
Technical inquiry about: 3D-FA110583 Ac-Ile-Glu-Thr-Asp-AMC
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