Ac-Gly-Pro-AFC

CAS: 886993-02-8

Ref. 3D-FA110612

Product Information

• Name: Ac-Gly-Pro-AFC
• CAS: 886993-02-8

Description

Ac-Gly-Pro-AFC is a dipeptidyl peptidase inhibitor that inhibits the action of protein-degrading enzymes called peptidases. Ac-Gly-Pro-AFC has been shown to be effective in treating diabetes by inhibiting the activity of fibroblast activation protein, which is involved in the development of diabetes. Ac-Gly-Pro-AFC also has an inhibitory effect on the enzyme connect, which is involved in cellular proliferation and differentiation. Clinical trials have been conducted to evaluate the efficacy of this drug for treatment of diabetic nephropathy with promising results. Ac-Gly-Pro-AFC has also been shown to have a beneficial effect on collagen synthesis and inhibition of proinflammatory cytokine release from activated macrophages.

• Brand: Biosynth

Chemical properties

• Molecular weight: 425.36 g/mol
• Formula: C₁₉H₁₈F₃N₃O₅
• Purity: Min. 95%
• InChI: InChI=1S/C19H18F3N3O5/c1-10(26)23-9-16(27)25-6-2-3-14(25)18(29)24-11-4-5-12-13(19(20,21)22)8-17(28)30-15(12)7-11/h4-5,7-8,14H,2-3,6,9H2,1H3,(H,23,26)(H,24,29)/t14-/m0/s1
• InChI key: InChIKey=SKKLIRUAUNZTRY-AWEZNQCLSA-N
• SMILES: CC(=O)NCC(=O)N1CCC[C@H]1C(=O)Nc1ccc2c(C(F)(F)F)cc(=O)oc2c1