4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt

CAS: 124168-73-6

Ref. 3D-FA111048

Product Information

• Name: 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt
• Synonyms: FN-439, MMP Inhibitor 1, 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH, p-Aminobenzyl-Gly-Pro-D-Leu-D-Ala Hydroxamic acid, N-[(4-aminophenyl)carbonyl]glycyl-L-prolyl-D-leucyl-N-hydroxy-D-alaninamide, MMP Inhibitor I
• CAS: 124168-73-6

Description

4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt is a synthetic, hydroxamic acid that inhibits the activity of collagenase, gelatinase and stromelysin. It also has inhibitory activities against metalloproteinases, such as matrix metalloproteinases and serine proteinases. 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt has been shown to inhibit the production of proinflammatory cytokines in human skin fibroblasts. This agent also induces the production of granulocytes in vitro.

• Brand: Biosynth

Chemical properties

• Molecular weight: 490.55 g/mol
• Formula: C₂₃H₃₄N₆O₆
• Purity: Min. 95%
• InChI: InChI=1S/C23H34N6O6/c1-13(2)11-17(22(33)26-14(3)20(31)28-35)27-23(34)18-5-4-10-29(18)19(30)12-25-21(32)15-6-8-16(24)9-7-15/h6-9,13-14,17-18,35H,4-5,10-12,24H2,1-3H3,(H,25,32)(H,26,33)(H,27,34)(H,28,31)
• InChI key: InChIKey=WWHUHFFMOPIVKB-UHFFFAOYSA-N
• SMILES: CC(C)CC(NC(=O)C1CCCN1C(=O)CNC(=O)c1ccc(N)cc1)C(=O)NC(C)C(=O)NO