1-(2-Anilino-4-methyl-1,3-thiazol-5-yl)ethanone

CAS: 31609-42-4

Ref. 3D-FA131091

Product Information

• Name: 1-(2-Anilino-4-methyl-1,3-thiazol-5-yl)ethanone
• Synonyms: 1-[4-Methyl-2-(phenylamino)-5-thiazolyl]-ethanone
• Brand: Biosynth
• Description: 1-(2-Anilino-4-methyl-1,3-thiazol-5-yl)ethanone is an antibacterial agent that inhibits bacterial growth by binding to the cell membrane. It has been shown to modulate the activity of a number of different antibiotics. This molecule has also been found to have a kinetic interaction with the enzyme cerulenin and has been used in optimization strategies for ligand synthesis. 1-(2-Anilino-4-methyl-1,3-thiazol-5-yl)ethanone is hydrophobic and binds tightly to the bacterial membrane, which may be due to its ability to form hydrogen bonds with the cell membrane or its steric properties. 1-(2-Anilino-4-methyl-1,3 -thiazol 5 yl)ethanone also binds to a receptor site on the bacterial cell surface and this binding leads to an increase in resistive energy.

Chemical properties

• Molecular weight: 232.3 g/mol
• Formula: C₁₂H₁₂N₂OS
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C12H12N2OS/c1-8-11(9(2)15)16-12(13-8)14-10-6-4-3-5-7-10/h3-7H,1-2H3,(H,13,14)
• InChI key: InChIKey=UIIUOFPGDKBCEZ-UHFFFAOYSA-N
• SMILES: CC(=O)c1sc(Nc2ccccc2)nc1C