2-Amino-5(6)-benzoylbenzimidazole

CAS: 52329-60-9

Ref. 3D-FA17593

Product Information

• Name: 2-Amino-5(6)-benzoylbenzimidazole
• Synonyms: (2-Amino-1H-benzimidazol-6-yl)phenylmethanone(2-Amino-1H-benzimidazol-5-yl)phenylmethanoneG 1029, (2-Amino-1H-benzimidazol-5-yl)phenylmethanone, (2-Amino-1H-benzimidazol-6-yl)phenylmethanone, (2-Amino-3H-benzimidazol-5-yl)-phenylmethanone, (2-amino-1H-benzimidazol-5-yl)(phenyl)methanone, 2-Amino-5-benzoyl-1H-benzimidazole, 2-Amino-5-benzoylbenzimidazole, Aminomebendazole, G 1029, R 18986, methanone, (2-amino-1H-benzimidazol-5-yl)phenyl-, methanone, (2-amino-1H-benzimidazol-6-yl)phenyl-

Description

2-Amino-5(6)-benzoylbenzimidazole is an antifilarial and anthelmintic drug that belongs to the benzimidazole class. It is used for the treatment of filarial infections in humans, including lymphatic filariasis, which is caused by worms transmitted by mosquitoes. 2-Amino-5(6)-benzoylbenzimidazole has low bioavailability due to its poor water solubility. The drug can be administered orally or topically and is metabolized in the liver. The metabolites are excreted in urine as glucuronides and sulfates.

• Brand: Biosynth

Chemical properties

• Molecular weight: 237.26 g/mol
• Formula: C₁₄H₁₁N₃O
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C14H11N3O/c15-14-16-11-7-6-10(8-12(11)17-14)13(18)9-4-2-1-3-5-9/h1-8H,(H3,15,16,17)
• InChI key: InChIKey=GPMHHSJZGVOEFS-UHFFFAOYSA-N
• SMILES: Nc1nc2ccc(C(=O)c3ccccc3)cc2[nH]1