2-Amino-4'-chloroacetophenone hydrochloride

CAS: 5467-71-0

Ref. 3D-FA55395

Product Information

• Name: 2-Amino-4'-chloroacetophenone hydrochloride
• Synonyms: 2-Amino-1-(4-chlorophenyl)-1-ethanone hydrochloride, 2-Amino-1-(4-chlorophenyl)ethanone hydrochloride, 2-Amino-4'-Chloroacetophenone Hydrochloride, 2-Amino-4'-chloroacetophenone HCl, 2-Amino-4'-chloroacetophenonehydrochloride, Acetophenone,2-amino-4'-chloro-, hydrochloride, Ethanone,2-amino-1-(4-chlorophenyl)-, hydrochloride, a-Amino-4-chloroacetophenonehydrochloride, a-Amino-p-chloroacetophenonehydrochloride, p-Chlorophenacylamine hydrochloride, α-Amino-4-chloroacetophenone hydrochloride, α-Amino-p-chloroacetophenone hydrochloride
• CAS: 5467-71-0

Description

2-Amino-4'-chloroacetophenone hydrochloride is a cytotoxic compound that inhibits the polymerization of tubulin. It has been shown to have cytotoxic effects and inhibit the growth of cancer cells in vitro at low micromolar concentrations. 2-Amino-4'-chloroacetophenone hydrochloride is a member of the cytotoxic class of compounds and can be used to slow or stop cell division by inhibiting the production of proteins vital for cell division, such as tubulin. This effect is due to its ability to bind to the beta subunit of tubulin, which disrupts its structure and prevents polymerization from occurring.

• Brand: Biosynth

Chemical properties

• Molecular weight: 206.07 g/mol
• Formula: C₈H₈ClNO•HCl
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C8H8ClNO/c9-7-3-1-6(2-4-7)8(11)5-10/h1-4H,5,10H2
• InChI key: InChIKey=KIFWACLIANOVDG-UHFFFAOYSA-N
• SMILES: NCC(=O)c1ccc(Cl)cc1