Boc-D-Arg(Pmc)-OH
CAS: 214630-02-1
Ref. 3D-FB111262
| 1g | 336.00 € | ||
| 2g | 526.00 € | ||
| 5g | 968.00 € | ||
| 10g | 1,607.00 € | ||
| 500mg | 215.00 € |
Product Information
- Boc-D-Arginine(Pmc)-Oh
- Boc-N-Omega-(2,2,4,6,7-Pentamethylchroman-6-Sulfonyl)-D-Arginine
- N-Alpha-T-Butoxycarbonyl-N-Omega-(2,2,5,7,8-Pentamethylchroman-6-Sulfonyl)-D-Arginine
- D-Ornithine, N5-[[[(3,4-Dihydro-2,2,5,7,8-Pentamethyl-2H-1-Benzopyran-6-Yl)Sulfonyl]Amino]Iminomethyl]-N2-[(1,1-Dimethylethoxy)Carbonyl]-
Boc-D-Arg(Pmc)-OH is a triazole derivative that inhibits the production of proinflammatory cytokines. It is used as a therapeutic for premature infants to reduce the risk of infections, such as sepsis and meningitis. Boc-D-Arg(Pmc)-OH has been shown to inhibit interleukin 1 receptor (IL1R) and IL1β synthesis in human cells. Boc-D-Arg(Pmc)-OH binds to the triazole ring of IL1β, preventing the formation of an enzyme complex that is required for IL1β synthesis. This binding also prevents the formation of an enzyme complex that is required for IL1R synthesis. The conformation of the peptide chain may be important for its activity, with some stereoisomers being more potent than others.
Chemical properties
Technical inquiry about: 3D-FB111262 Boc-D-Arg(Pmc)-OH
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