1,5-Bis(4-allyldimethylammoniumphenyl)pentan-3-one, dibromide

CAS: 402-40-4

Ref. 3D-FB18689

Product Information

• Name: 1,5-Bis(4-allyldimethylammoniumphenyl)pentan-3-one, dibromide
• Synonyms: 4,4'-(3-Oxo-1,5-pentanediyl)bis[N,N-dimethyl-N-2-propen-1-yl-benzenaminium bromide, 1,5-Bis(p-N-allylmethylaminophenyl)-pentan-3-one dimethylbromide, 1,5-Bis-(4-allyldimethylammoniumphenyl)-pentane-3-one dibromide, 1,5-Bis[4-(allyldimethylammonium)phenyl]pentan-3-one dibromide, 4,4'-(3-oxopentane-1,5-diyl)bis[N,N-dimethyl-N-(prop-2-en-1-yl)anilinium] dibromide, Ammonium, [(3-oxopentamethylene)di-p-phenylene]bis[allyldimethyl-, dibromide, Benzenaminium, 4,4′-(3-oxo-1,5-pentanediyl)bis[N,N-dimethyl-N-2-propen-1-yl-, bromide (1:2), Benzenaminium, 4,4′-(3-oxo-1,5-pentanediyl)bis[N,N-dimethyl-N-2-propenyl-, dibromide, Bw 284, Bw 284C51, [(3-Oxopentamethylene)di-p-phenylene]bis[allyldimethylammonium bromide]

Description

1,5-Bis(4-allyldimethylammoniumphenyl)pentan-3-one, dibromide is a reversible inhibitor of acetylcholinesterase. It has been shown to inhibit the enzyme activity in vitro and in vivo. 1,5-Bis(4-allyldimethylammoniumphenyl)pentan-3-one, dibromide has been shown to be an effective inhibitor of nicotinic acetylcholine receptors in model organisms such as Xenopus oocytes and Acetylcholine esterase activated rat pheochromocytoma cells. The molecule also inhibits the phosphorylation of pnitrophenyl phosphate by choline kinase. This inhibiting effect on choline kinase leads to a decrease in the concentration of choline available for neurotransmitter synthesis. Monoclonal antibodies against acetylcholinesterase are used to detect this

• Brand: Biosynth

Chemical properties

• Molecular weight: 566.41 g/mol
• Formula: C₂₇H₃₈Br₂N₂O
• Purity: Min. 95%