tert-Butyl cis-4-hydroxycyclohexylcarbamate

CAS: 167081-25-6

Ref. 3D-FB56961

Product Information

• Name: tert-Butyl cis-4-hydroxycyclohexylcarbamate
• Synonyms: cis-N-Boc-4-amino-cyclohexanol
• Brand: Biosynth
• Description: Tert-butyl cis-4-hydroxycyclohexylcarbamate is a pharmacological agent that has been shown to have anticonvulsant activity. It is a phenytoin amide that has neurotoxic effects and can cause convulsions. Tert-butyl cis-4-hydroxycyclohexylcarbamate binds to the sulfonamide site on the enzyme GABA transaminase, which converts GABA into succinic semialdehyde, thereby inhibiting the synthesis of GABA. This drug also inhibits the production of acetaldehyde from ethanol by preventing oxidation of NADH and NADPH. The tert-butyl cis-4-hydroxycyclohexylcarbamate was found to have an anticonvulsant effect in animals when given intravenously and orally. It also showed a protective effect against electroshock seizures in rats, suggesting an anticonvulsant activity.

Chemical properties

• Molecular weight: 215.29 g/mol
• Formula: C₁₁H₂₁NO₃
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-8-4-6-9(13)7-5-8/h8-9,13H,4-7H2,1-3H3,(H,12,14)
• InChI key: InChIKey=DQARDWKWPIRJEH-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NC1CCC(O)CC1