µ-Conotoxin GIIIB
CAS: 140678-12-2
Ref. 3D-FC110369
| 1mg | 1,725.00 € | ||
| 50µg | 220.00 € | ||
| 100µg | 359.00 € | ||
| 250µg | 636.00 € | ||
| 500µg | 1,053.00 € |
Product Information
- H-Arg-Asp-Cys-Cys-Thr-Hyp-Hyp-Arg-Lys-Cys-Lys-Asp-Arg-Arg-Cys-Lys-Hyp-Met-Lys-Cys-Cys-Ala-NH2 H-RDCCT(hyP)(hyP)RKCKDRRCK(hyP)MKCCA- NH2
- Conotoxin GIIIB
- H-Arg-Asp-Cys-Cys-Thr-Hyp-Hyp-Arg-Lys-Cys-Lys-Asp-Arg-Arg-Cys-Lys-Hyp-Met-Lys-Cys-Cys-Ala-NH2 (Disulfide bonds between Cys3 and Cys15/Cys4 and Cys20/ Cys10 and Cys21)
- Mu-Conotoxin Giiib
The µ-conotoxin GIIIB is a potent nicotinic acetylcholine receptor antagonist and has been shown to inhibit the g1 phase of the cell cycle. It inhibits the binding of veratridine, a neurotoxin, to its receptor on the cell membrane. The µ-conotoxin GIIIB has also been shown to have an inhibitory effect on acetylcholine release from synaptosomes incubated with glucose and insulin. A magnetic resonance spectroscopy (MRS) study showed that µ-conotoxin GIIIB was able to bind to noradrenaline and dopamine receptors in rat erythrocytes. The µ-conotoxin GIIIB is a disulfide bond peptide that can be synthesized by solid-phase synthesis and purified by lc-ms/ms methods. Disulfide bonds are formed between Cys3 and Cys15, Cys4 and Cys20, Cys10
Chemical properties
Technical inquiry about: 3D-FC110369 µ-Conotoxin GIIIB
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