Cefprozil - mix of Z (92%), and E (7%) isomers

CAS: 92665-29-7

Ref. 3D-FC19868

Product Information

• Name: Cefprozil - mix of Z (92%), and E (7%) isomers
• Synonyms: (6R,7R)-7-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-(1-propen-1-yl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic a cidBMY 28100Cefprozile
• Brand: Biosynth
• Description: Cefprozil is a bactericidal antibiotic that belongs to the group of cephalosporin antibiotics. It is used to treat bacterial infections, such as respiratory and urinary tract infections, otitis media, skin and soft tissue infections. Cefprozil inhibits bacterial growth by binding to one or more penicillin-binding proteins (PBPs), which are proteins on the surface of bacteria that bind to β-lactam antibiotics and help them enter the cell. This drug has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) in vitro. In addition, it has been shown that cefprozil binds to plasma proteins, including albumin and α1-acid glycoprotein, with high affinity. Cefprozil is metabolized by human cytochrome P450 enzymes into inactive metabolites that are excreted in urine. The metabolism of cefprozil can be inhibited by

Chemical properties

• Molecular weight: 389.43 g/mol
• Formula: C₁₈H₁₉N₃O₅S
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C18H19N3O5S/c1-2-3-10-8-27-17-13(16(24)21(17)14(10)18(25)26)20-15(23)12(19)9-4-6-11(22)7-5-9/h2-7,12-13,17,22H,8,19H2,1H3,(H,20,23)(H,25,26)/b3-2+/t12-,13-,17-/m1/s1
• InChI key: InChIKey=WDLWHQDACQUCJR-ZAMMOSSLSA-N
• SMILES: C/C=C/C1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccc(O)cc3)[C@H]2SC1