Vismodegib
CAS: 879085-55-9
Ref. 3D-FC28712
| 1g | 276.00 € | ||
| 5g | 739.00 € | ||
| 10g | 1,192.00 € | ||
| 250mg | 118.00 € | ||
| 500mg | 186.00 € |
Estimated delivery in United States, on Monday 13 May 2024
Product Information
Name:
Vismodegib
Synonyms:
- GDC 04492-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
- 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
- Benzamide, 2-Chloro-N-[4-Chloro-3-(2-Pyridinyl)Phenyl]-4-(Methylsulfonyl)-
- Erivedge
- Gdc-0449
- Vismodegib (GDC-0449)
CAS:
Description:
Vismodegib is a Hedgehog (Hh) pathway inhibitor belonging to the 2-arylpyridine class. It acts as a competitive antagonist of the smoothened receptor (SMO) localized in the cell membrane. SMO activates an intracellular cascade that results in activation and nuclear translocation of Gli family transcription factor. Vismodegib has been used in clinical trials for treatment of advanced cancers.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
420.01022
Formula:
C19H14Cl2N2O3S
Purity:
Min. 95%
Color/Form:
Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: 3D-FC28712 Vismodegib
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