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Coelenterazine F
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Coelenterazine F

CAS: 123437-16-1

Ref. 3D-FC30724

1mg
245.00 €
2mg
383.00 €
5mg
538.00 €
10mg
811.00 €
25mg
1,801.00 €
Estimated delivery in United States, on Tuesday 23 Apr 2024

Product Information

Name:
Coelenterazine F
Synonyms:
  • Coelenterazine-fluoride8-Benzyl-2-(4-fluorobenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-α]pyrazin-3(7H)-one
  • 2-(P-Fluorobenzyl)-6-(P-Hydroxyphenyl)-8-Benzylimidazo[1,2-A]Pyrazin-3-(7H)-One
  • 2-(P-Fluorobenzyl)-6-(P-Hydroxyphenyl)-8-Benzylimidazo[1,2-A]Pyrazine-3-(7H)-One
  • Clz-F
  • Clzn-F
  • Coelenterazine-F, Synthetic
  • 8-benzyl-2-(4-fluorobenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one
Description:

Coelenterazine F is a light-emitting molecule that has been shown to emit light when it binds to cytosolic Ca2+. In addition, it can be used in the detection of Ca2+ changes. The molecular structure consists of two disulfide bonds and a reactive cysteine residue that can form covalent bonds with other molecules. This reaction releases energy in the form of light. Coelenterazine F has been shown to produce fluorescence resonance energy transfer (FRET) with luciferase, which is a reconstituted protein complex that emits light when oxidized by coelenterazine F. Coelenterazine F has also been shown to induce pro-inflammatory cytokines, such as IL-6 and TNF-α, which are involved in inflammatory response.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
425.45 g/mol
Formula:
C26H20FN3O2
Purity:
Min. 95 Area-%
Color/Form:
Orange Powder
InChI:
InChI=1S/C26H20FN3O2/c27-20-10-6-18(7-11-20)15-23-26(32)30-16-24(19-8-12-21(31)13-9-19)28-22(25(30)29-23)14-17-4-2-1-3-5-17/h1-13,16,31-32H,14-15H2
InChI key:
InChIKey=MEMQQZHHXCOKGG-UHFFFAOYSA-N
SMILES:
Oc1ccc(-c2cn3c(O)c(Cc4ccc(F)cc4)nc3c(Cc3ccccc3)n2)cc1
MDL:
Melting point:
Boiling point:
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Density:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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