DABCYL-Lys-HCoV-SARS Replicase Polyprotein 1ab (3235-3246)-Glu-EDANS trifluoroacetate salt
CAS:
Ref. 3D-FD110979
1mg
1,217.00€
2mg
2,091.00€
5mg
3,694.00€
Product Information
Name:DABCYL-Lys-HCoV-SARS Replicase Polyprotein 1ab (3235-3246)-Glu-EDANS trifluoroacetate salt
Synonyms:
- DABCYL-Lys-pp1ab (3235-3246)-Glu-EDANS (Human coronavirus) (strain SARS)
- DABCYL-Lys-ORF1AB (3235-3246)-Glu-EDANS (Human coronavirus ) (strain SARS)
Brand:Biosynth
Description:DABCYL-Lys-HCoV-SARS Replicase Polyprotein 1ab (3235-3246)-Glu-EDANS trifluoroacetate salt is a fluorescent substrate for the SARS coronavirus. This compound is an inhibitor of the enzyme that is the target of a drug candidate that inhibits the replication of this virus. Molecular docking studies have shown that DABCYL-Lys-HCoV-SARS Replicase Polyprotein 1ab (3235-3246)-Glu-EDANS trifluoroacetate salt binds to 3clpro, which is part of the active site of the enzyme’s catalytic pocket. Inhibition activity was seen in experiments using recombinant proteins, and kinetic analysis showed this inhibitor has a Ki value of 0.7 mM.
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Chemical properties
Molecular weight:2,195.47 g/mol
Formula:C95H141N25O24S2·C2HF3O2
Purity:Min. 95 Area-%
Color/Form:Powder
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