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4-Deoxypodophyllotoxin
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4-Deoxypodophyllotoxin

CAS: 19186-35-7

Ref. 3D-FD157413

5mg
108.00 €
10mg
148.00 €
25mg
200.00 €
50mg
334.00 €
100mg
501.00 €
Estimated delivery in United States, on Monday 13 May 2024

Product Information

Name:
4-Deoxypodophyllotoxin
Synonyms:
  • Desoxypodophyllotoxin
  • (-)-Anthricin
  • (5R,5aR,8aR)-5,8,8a,9-Tetrahydro-5-(3,4,5-trimethoxyphenyl)furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
  • As 2-3
  • Deoxypodophyllotoxin
  • Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-, (5R,5aR,8aR)-
  • Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-, (5R,5aR,8aR)-
  • Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-, [5R-(5α,5aβ,8aα)]-
  • Podophyllotoxin, deoxy-
  • Silicicolin
  • See more synonyms
Description:

Podophyllotoxin is a natural compound that has been shown to inhibit the polymerase chain reaction (PCR) by binding to DNA. Podophyllotoxin also inhibits cell proliferation in human leukemia HL-60 cells and breast cancer cells, as well as autophagy in K562 cells. Podophyllotoxin can potentiate the activity of drugs such as dimethyl fumarate and toll-like receptor (TLR) agonists, which are used for the treatment of various other cancers. Podophyllotoxin has been shown to induce mitochondrial membrane potential changes, which are associated with apoptosis induction. This drug has also been shown to be an experimental model for resistant breast cancer.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
398.41 g/mol
Formula:
C22H22O7
Purity:
Min. 95%
Color/Form:
White Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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