Efinaconazole

CAS: 164650-44-6

Ref. 3D-FD58714

Product Information

• Name: Efinaconazole
• Synonyms: (αR,βR)-α-(2,4-Difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol, (2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(4H-1,3,4-triazol-4-yl)butan-2-ol, (R,R)-2-(2,4-Difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)-2-butanol, 1-Piperidineethanol, α-(2,4-difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-, (αR,βR)-, 1-Piperidineethanol, α-(2,4-difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-, [R-(R*,R*)]-, Jublia, KP 103 (pharmaceutical), Kp-103
• CAS: 164650-44-6

Description

Efinaconazole is a synthetic antifungal agent that is active against dermatophytes, yeasts and molds. It is a new generation triazole with potent in vitro antifungal activity and long-term efficacy. Efinaconazole has been shown to be effective against Candida albicans, Candida dubliniensis, Candida glabrata, Candida parapsilosis, Candida tropicalis, and Trichophyton mentagrophytes. The pharmacokinetic properties of efinaconazole have been studied using LC-MS/MS method. These results showed that the drug is well absorbed after oral administration and has a half-life of about 2 hours. In addition, this drug does not show any significant interactions with other drugs or food products. Efinaconazole can be used for the treatment of skin lesions caused by candidiasis or tinea corporis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 348.39 g/mol
• Formula: C₁₈H₂₂F₂N₄O
• Purity: Min. 98 Area-%
• Color/Form: Powder