Product Information
(R)-Simurosertib is a ligand that binds to the beta-2 adrenergic receptor. It has been shown to activate the receptor and increase cAMP levels in cell lines, which can lead to an increase in lysosomal enzyme secretion. (R)-Simurosertib also inhibits protein interactions in the endoplasmic reticulum by binding to the hydrophobic pocket of proteins. This binding prevents protein folding and causes aggregation, which leads to cell death.
Chemical properties
Technical inquiry about: 3D-FDC78269 (R)-Simurosertib
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