Ethyl 2-methylthiophene-3-carboxylate

CAS: 19432-66-7

Ref. 3D-FE139396

Product Information

• Name: Ethyl 2-methylthiophene-3-carboxylate
• Synonyms: 3-Thiophenecarboxylic Acid, 2-Methyl-, Ethyl Ester, Ethyl 2-Methylthiophene-3-Carboxylate

Description

Ethyl 2-methylthiophene-3-carboxylate is an intermediate in the synthesis of a variety of organic compounds, including fluoroalcohols and pharmaceuticals. The synthesis is based on the Wittig reaction, which involves the formation of a wittig reagent from a magnesium halide and a carboxylic acid chloride. This reagent reacts with an aromatic compound such as thiophene to form an alkyl group at the α position. The alkylation proceeds intramolecularly to form ethyl 2-methylthiophene-3-carboxylate without any need for an external base. Ethyl 2-methylthiophene-3-carboxylate can be obtained through a scalable, efficient method that uses Grignard reagents as starting materials.

• Brand: Biosynth

Chemical properties

• Molecular weight: 170.23 g/mol
• Formula: C₈H₁₀O₂S
• Purity: Min. 95%
• InChI: InChI=1S/C8H10O2S/c1-3-10-8(9)7-4-5-11-6(7)2/h4-5H,3H2,1-2H3
• InChI key: InChIKey=GNOBQWZOPPOTMC-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1ccsc1C