Emixustat

CAS: 1141777-14-1

Ref. 3D-FE171071

Product Information

• Name: Emixustat
• Synonyms: (aR)-a-(2-Aminoethyl)-3-(cyclohexylmethoxy)benzenemethanol
• CAS: 1141777-14-1

Description

Emixustat is a chemical inhibitor that inhibits the activity of the cation channel TRPM1. TRPM1 is expressed in choroidal neovascularization and proliferative diabetic retinopathy. It also has shown potential as a diagnostic agent for these eye disorders. Emixustat has been shown to inhibit the production of growth factors, which may be a cause for its therapeutic effect in both congenital amaurosis and growth factor-related eye disorders. Emixustat is an investigational drug that has not been approved by the FDA yet, but it is currently in phase III clinical trials.

• Brand: Biosynth

Chemical properties

• Molecular weight: 263.38 g/mol
• Formula: C₁₆H₂₅NO₂
• Purity: Min. 95%
• Color/Form: Colourless To Yellow Liquid
• InChI: InChI=1S/C16H25NO2/c17-10-9-16(18)14-7-4-8-15(11-14)19-12-13-5-2-1-3-6-13/h4,7-8,11,13,16,18H,1-3,5-6,9-10,12,17H2/t16-/m1/s1
• InChI key: InChIKey=WJIGGYYSZBWCGC-MRXNPFEDSA-N
• SMILES: NCC[C@@H](O)c1cccc(OCC2CCCCC2)c1