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2-Ethyl-2-phenylmalonamide
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2-Ethyl-2-phenylmalonamide

CAS: 7206-76-0

Ref. 3D-FE23105

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Estimated delivery in United States, on Wednesday 22 May 2024

Product Information

Name:
2-Ethyl-2-phenylmalonamide
Synonyms:
  • 2-Ethyl-2-phenyl-propanediamide2-Ethyl-2-phenylmalondiamidePhenylethylmalonamide
  • 2-Ethyl-2-Phenylmalonamide
  • 2-Ethyl-2-Phenylmalondiamide
  • 2-Ethyl-2-Phenylpropanediamide
  • 2-Ethyl-2-Phenylpropanediamide Hydrate
  • 2-Methyl-2-Phenylbutanamide
  • 2-Phenyl-2-Ethylmalonamide
  • 2-Phenyl-2-Ethylmalondiamide
  • Ethylphenylmalondiamide
  • Malonamide, 2-ethyl-2-phenyl-
  • See more synonyms
  • PEMA monohydrate
  • Pema
  • Pema (Amide)
  • Phenylethylmalonamide
  • Phenylethylmalondiamide
  • Propanediamide, 2-ethyl-2-phenyl-
Description:

2-Ethyl-2-phenylmalonamide (2-EPMA) is a metabolite of primidone that acts as an inhibitor of glutamate dehydrogenase and may be used in the treatment of epilepsy. It has been shown to be effective in treating seizures caused by carbamazepine, phenobarbital, or phenytoin. 2-EPMA is also used to measure enzyme activities in serum, which can be used as a diagnostic tool for liver diseases. 2-EPMA is typically prepared for use as an enzyme inhibitor by diluting it with high salt or human serum. This compound may have carcinogenic potential and should not be administered with single doses greater than 100 mg/kg body weight. 2-EPMA interacts with many other drugs such as phenobarbital, phenytoin, and carbamazepine.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
206.24 g/mol
Formula:
C11H14N2O2
Purity:
Min. 95%
InChI:
InChI=1S/C11H14N2O2/c1-2-11(9(12)14,10(13)15)8-6-4-3-5-7-8/h3-7H,2H2,1H3,(H2,12,14)(H2,13,15)
InChI key:
InChIKey=JFZHPFOXAAIUMB-UHFFFAOYSA-N
SMILES:
CCC(C(N)=O)(C(N)=O)c1ccccc1
MDL:
Melting point:
Boiling point:
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Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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