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E-64-c
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E-64-c

CAS: 76684-89-4

Ref. 3D-FE29622

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Estimated delivery in United States, on Thursday 23 May 2024

Product Information

Name:
E-64-c
Synonyms:
  • (+)-(2S,3S)-3-((S)-3-Methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxiranecarboxylic acid
  • (2S,3S)-3-({(2S)-4-methyl-1-[(3-methylbutyl)amino]-1-oxopentan-2-yl}carbamoyl)oxirane-2-carboxylic acid
  • (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic acid
  • 2-Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, (2S,3S)-
  • Brn 6688621
  • E 64c
  • EP 475 (Enzyme inhibitor)
  • Ep 475
  • Loxistatin acid
  • NSC 694279
  • See more synonyms
  • Oxiranecarboxylic acid, 3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)amino)carbonyl)-, (2S-(2-alpha,3-beta(R*)))-
  • Oxiranecarboxylic acid, 3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)amino)carbonyl)-, (2S-(2alpha,3beta(R*)))-
  • Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, (2S,3S)-
  • Oxiranecarboxylic acid, 3-[[[3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, [2S-[2α,3β(R*)]]-
Description:

E-64-c is a potent proteolytic enzyme that is used in the treatment of breast cancer. E-64-c cleaves peptide hormones and bcr-abl kinase, which are involved in the development of cancer cells. It can also be used to inhibit the activity of other enzymes, such as phospholipase A2 and cyclooxygenase. The mechanism behind its action is not known, but it may be due to chemical inhibition or reversible denaturation. Chemotherapy drugs that are used to treat breast cancer include doxorubicin, daunorubicin, epirubicin, idarubicin, mitoxantrone, and vincristine.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
314.38 g/mol
Formula:
C15H26N2O5
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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