Endomorphin-2
CAS: 141801-26-5
Ref. 3D-FE73364
| 1mg | To inquire | |
| 2mg | To inquire | |
| 5mg | To inquire | |
| 10mg | To inquire | |
| 25mg | To inquire |
Product Information
- Endomorphin-2 (Human, Bovine)
- Ypff-Nh2
- Tyr-Pro-Phe-Phe-Nh2
- (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(1S)-1-[[(1S)-1-carbamoyl-2-phenyl-ethyl]carbamoyl]-2-phenyl-ethyl]pyrrolidine-2-carboxamide
- L-tyrosyl-L-prolyl-L-phenylalanyl-L-phenylalaninamide
Endomorphin-2 is a cyclic peptide that has been shown to have analgesic and anti-inflammatory effects. It binds to the kappa-opioid receptor and inhibits locomotion in mice. It also has shown to be effective at treating bowel disease in vivo models. The biological properties of endomorphin-2 include its ability to stimulate the release of neurokinin-1 from trigeminal nerve endings, which then stimulates the release of substance P from sensory neurons. Endomorphin-2 does not bind to receptors for endomorphin 1 or endomorphin 3, but it does bind with high affinity to the neurokinin-1 receptor.
Chemical properties
Technical inquiry about: 3D-FE73364 Endomorphin-2
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