Endothelin-1, human
CAS: 117399-94-7
Ref. 3D-FE73365
| 1mg | To inquire | |
| 50µg | To inquire | |
| 100µg | To inquire | |
| 250µg | To inquire | |
| 500µg | To inquire |
Product Information
- Endothelin 1 human, porcine
- H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11)
- Endothelin 1, Human and Porcine
- Endothelin-1,Human
Endothelin-1, human is a protein that belongs to the endothelin family of peptides. It is a potent vasoconstrictor and has been implicated in a number of biological processes such as blood pressure regulation, bowel disease, and pulmonary hypertension. Endothelin-1, human is produced by the endothelial cells in response to injury or other stimuli. The production of this peptide can be modulated by epigenetic modifiers. Endothelin-1, human has been shown to have significant upregulation in squamous cell carcinoma cells and primary pulmonary hypertension patients. The function of endothelin-1, human is mediated by its receptor (ET) which binds to guanine nucleotide binding proteins (G proteins).
Chemical properties
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