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FA-Leu-Gly-Pro-Ala-OH
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FA-Leu-Gly-Pro-Ala-OH

CAS: 78832-65-2

Ref. 3D-FF110857

1mg
174.00 €
2mg
242.00 €
5mg
340.00 €
10mg
499.00 €
25mg
706.00 €
Estimated delivery in United States, on Monday 22 Apr 2024

Product Information

Name:
FA-Leu-Gly-Pro-Ala-OH
Synonyms:
  • FALGPA
  • N-(3-(2-furyl)acryloyl)-leu-gly-pro-ala
  • Falgpa
  • N-[(2E)-3-furan-2-ylprop-2-enoyl]-L-leucylglycyl-L-prolyl-L-alanine
Description:

FA-Leu-Gly-Pro-Ala-OH is a gelatinase inhibitor that inhibits the action of collagenase, an enzyme that breaks down collagen. It has been shown to inhibit the growth of cancer cells in vitro and may be useful as a therapeutic agent against skin cancer. FA-Leu-Gly-Pro-Ala-OH binds to the active site of the enzyme and blocks its catalytic activity by preventing proton transfer during the hydrolysis of peptide bonds. This inhibitor also has proteolytic properties, which are due to its ability to cleave proteins with basic amino acids such as arginine and lysine. The inhibitory effects of FA-Leu-Gly-Pro-Ala-OH on histological analysis were also tested on fibroblast cells with collagenase activity, which showed a significant reduction in enzyme activity after incubation with this inhibitor.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
476.52 g/mol
Formula:
C23H32N4O7
Purity:
Min. 95%
Color/Form:
Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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