Fmoc-D-Leu-OH

CAS: 114360-54-2

Ref. 3D-FF39046

Product Information

• Name: Fmoc-D-Leu-OH
• Synonyms: NALPHA-9-Fluorenylmethoxycarbonyl-D-leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-leucine
• CAS: 114360-54-2

Description

Fmoc-D-Leu-OH is a disulfide bond containing molecule with an intracellular Ca2+ chelating activity. It has been shown to have cytoprotective effects against oxidative stress and cell death, and has also been found to have antiinflammatory properties. Fmoc-D-Leu-OH can inhibit the activities of various enzymes such as cyclooxygenase, lipoxygenase, phospholipases, and diamine oxidase. This molecule also exhibits cytotoxic activity against bladder cancer cells in vitro. The pharmacokinetic properties of Fmoc-D-Leu-OH are similar to other molecules that are used as antibiotics.
Fmoc-D-Leu-OH is a cyclic peptide with antimicrobial peptide (AMP) activity that inhibits bacterial growth by disrupting their cell membranes or inhibiting protein synthesis. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading

• Brand: Biosynth

Chemical properties

• Molecular weight: 353.41 g/mol
• Formula: C₂₁H₂₃NO₄
• Purity: Min. 98 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m1/s1
• InChI key: InChIKey=CBPJQFCAFFNICX-LJQANCHMSA-N
• SMILES: CC(C)C[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O