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Fmoc-D-Trp(Boc)-OH
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Fmoc-D-Trp(Boc)-OH

CAS: 163619-04-3

Ref. 3D-FF47371

2g
109.00 €
5g
188.00 €
10g
293.00 €
25g
477.00 €
50g
681.00 €
Estimated delivery in United States, on Tuesday 23 Apr 2024

Product Information

Name:
Fmoc-D-Trp(Boc)-OH
Synonyms:
  • Na-Fmoc-Nin-Boc-D-tryptophan
  • 1-(tert-butoxycarbonyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-tryptophan
Description:

Fmoc-D-Trp(Boc)-OH is a β-amino acid that has potent antitumor activity. It is a cyclic peptide that has been synthesized by solid-phase chemistry and molecular modelling. Fmoc-D-Trp(Boc)-OH inhibits the histone deacetylase (HDAC) enzyme, which controls gene expression and cell proliferation, and is a potential anticancer drug. This molecule also inhibits the uptake of kynurenine by cancer cells, leading to cell death. Fmoc-D-Trp(Boc)-OH has been shown to inhibit the growth of human breast cancer cells in culture with an IC50 of 10 μM and to induce apoptosis in these cells with an IC50 of 2 μM.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
526.58 g/mol
Formula:
C31H30N2O6
Purity:
Min. 95%
Color/Form:
Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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