Product Information
Name:Fmoc-L-homotyrosine
Synonyms:
- Fmoc-homo-L-tyrosine
Brand:Biosynth
Description:Fmoc-L-homotyrosine is a tyrosine kinase inhibitor. Tyrosine kinases are enzymes that catalyze the transfer of phosphate groups from ATP to tyrosine residues in proteins, which play a role in many cellular processes. Fmoc-L-homotyrosine binds to the ATP binding site in the active site of these enzymes, preventing phosphorylation and thus preventing protein function. This compound has been shown to inhibit neurotensin receptors in vitro and has also been shown to be an endogenous ligand for this receptor. Fmoc-L-homotyrosine binds to allosteric sites on the neurotensin receptor, causing conformational changes that activate transduction pathways and increase signaling. The mechanism of inhibition is not yet fully understood but is thought to be due to steric hindrance or allosteric binding.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:417.45 g/mol
Formula:C25H23NO5
Purity:Min. 95%
Technical inquiry about: Fmoc-L-homotyrosine
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