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4-[1-(3-Fluoro-4-Phenylphenyl)Ethyl]-N-Methyl-1,3-Thiazol-2-Amine
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4-[1-(3-Fluoro-4-Phenylphenyl)Ethyl]-N-Methyl-1,3-Thiazol-2-Amine

CAS: 113759-19-6

Ref. 3D-FF97789

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Estimated delivery in United States, on Monday 22 Apr 2024

Product Information

Name:
4-[1-(3-Fluoro-4-Phenylphenyl)Ethyl]-N-Methyl-1,3-Thiazol-2-Amine
Synonyms:
  • Sm 8849
  • 2-Thiazolamine, 4-(1-(2-fluoro(1,1'-biphenyl)-4-yl)ethyl)-N-methyl-
  • 4-[1-(2-fluorobiphenyl-4-yl)ethyl]-N-methyl-1,3-thiazol-2-amine
Description:

4-[1-(3-Fluoro-4-Phenylphenyl)Ethyl]-N-Methyl-1,3-Thiazol-2-Amine (MTX) is a nonsteroidal anti-inflammatory drug that inhibits adhesion formation in cells. It has been shown to be effective against inflammatory diseases such as arthritis and Crohn's disease. MTX is an inhibitor of the enzyme cyclooxygenase, which produces prostaglandins and thromboxanes from arachidonic acid. MTX is metabolized by conjugation with glucuronic acid, sulfate, or methyl groups. The metabolites are excreted in the urine and bile. MTX also inhibits collagen synthesis and monoclonal antibodies directed against collagen have been used to study its effects on the inhibition of adhesion molecule expression in inflammatory cells. The mechanism of action of MTX has been studied in knockout mice lacking specific key proteins involved in inflammation that

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
312.41 g/mol
Formula:
C18H17FN2S
Purity:
Min. 95%
InChI:
InChI=1S/C18H17FN2S/c1-12(17-11-22-18(20-2)21-17)14-8-9-15(16(19)10-14)13-6-4-3-5-7-13/h3-12H,1-2H3,(H,20,21)
InChI key:
InChIKey=ZTFDMDJGJVUYQE-UHFFFAOYSA-N
SMILES:
CNc1nc(C(C)c2ccc(-c3ccccc3)c(F)c2)cs1
MDL:
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EINECS:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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