H-Gly-Pro-Gly-OH

CAS: 2441-63-6

Ref. 3D-FG110452

Product Information

• Name: H-Gly-Pro-Gly-OH
• Synonyms: glycine, glycyl-L-prolyl-
• CAS: 2441-63-6

Description

H-Gly-Pro-Gly-OH is a glycan molecule. It is an artificially synthesized glycan that was designed to act as a neutralizing agent for HIV. It binds to the envelope protein gp120 and prevents it from binding to CD4 receptors on cells, thereby preventing viral entry into the cell. H-Gly-Pro-Gly-OH has also been shown to be effective in neutralizing collagenase activity, which may be useful in treating arthritis and other autoimmune disorders.
H-Gly-Pro-Gly-OH has been shown to bind to monoclonal antibodies that are used in the development of cancer treatments, such as Herceptin and Erbitux. This binding is thought to be due to sequences within the antibody that correspond with those found on gp120, the envelope protein of HIV.

• Brand: Biosynth

Chemical properties

• Molecular weight: 229.23 g/mol
• Formula: C₉H₁₅N₃O₄
• Purity: Min. 95%
• InChI: InChI=1S/C9H15N3O4/c10-4-7(13)12-3-1-2-6(12)9(16)11-5-8(14)15/h6H,1-5,10H2,(H,11,16)(H,14,15)/t6-/m0/s1
• InChI key: InChIKey=NSVOVKWEKGEOQB-LURJTMIESA-N
• SMILES: NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)O