H-Gly-Pro-pNA•hydrochloride
CAS: 103213-34-9
Ref. 3D-FG110792
| 25mg | 184.00 € | ||
| 50mg | 279.00 € | ||
| 100mg | 455.00 € | ||
| 250mg | 877.00 € | ||
| 500mg | 1,564.00 € |
Product Information
- glycyl-N-(4-nitrophenyl)prolinamide hydrochloride
H-Gly-Pro-pNA is an antidiabetic drug that inhibits the activity of dipeptidyl peptidase IV (DPP IV), a family of enzymes that catalyses the cleavage of the amino acid sequence of proline and arginine. The inhibitory effect on DPP IV by H-Gly-Pro-pNA was demonstrated using magnetic resonance spectroscopy, chromatographic assays, and electrospray ionization mass spectrometry. H-Gly-Pro-pNA also has hydrophobic properties and can interact with other drugs that are lipophilic. In vitro assays have been used to determine the inhibition activity of H-Gly-Pro-pNA against various proteins involved in diabetes mellitus, including aminopeptidases, carboxypeptidases and endopeptidases.
Chemical properties
Technical inquiry about: 3D-FG110792 H-Gly-Pro-pNA•hydrochloride
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