Glycine t-butyl ester hydrochloride

CAS: 27532-96-3

Ref. 3D-FG23689

Product Information

• Name: Glycine t-butyl ester hydrochloride
• Synonyms: Glycine 1,1-dimethylethyl ester hydrochloride1,1-Dimethylethyl glycinate hydrochlorideGlycine tert-butyl ester monohydrochloride, 1,1-Dimethylethyl glycinate hydrochloride, 2-(tert-Butoxy)-2-oxoethan-1-aminium chloride, 2-Aminoacetic acid tert-butyl ester hydrochloride, 2-Tert-Butoxy-2-Oxoethanaminium, GLYCIN-tert-butyl ester hydrochloride, GLYCINE T-butyl ester HCL, Glycine tert butyl ester hydrochloride, Glycine tert-butyl ester HCl, Glycine tert-butyl ester monohydrochloride, Glycine, 1,1-dimethylethyl ester, hydrochloride, Glycine, 1,1-dimethylethyl ester, hydrochloride (1:1), H-Gly-OtBu.HCl, H-Gly-OtBu・HCl, Tert-Butyl Glycinate Hydrochloride, tert-Butyl 2-aminoacetate hydrochloride, tert-Butylglycinate hydrochloride
• CAS: 27532-96-3

Description

Glycine t-butyl ester hydrochloride is a glycine prodrug that is converted to the neurotransmitter, cinchonidine, by carboxylesterase. It has been shown to be effective in resistant cancer cells and has good bioavailability in humans. Glycine t-butyl ester hydrochloride is synthesized from glycine and butyric acid with sodium carbonate as a catalyst and then reacted with anhydrous hydrogen chloride to form the final product. This synthesis requires an asymmetric reaction solution, which can be achieved by using a chiral reactant such as potassium carbonate or magnesium chloride. The dehydration of the ester group can be performed by heating in vacuum at 120°C for 2 hours.

• Brand: Biosynth

Chemical properties

• Molecular weight: 167.63 g/mol
• Formula: C₆H₁₄ClNO₂
• Purity: Min. 95%
• Color/Form: White Powder