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HIV-1 env Protein gp120 (278-292) (strains BH10, BH8, HXB2, HXB3, PV22)
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HIV-1 env Protein gp120 (278-292) (strains BH10, BH8, HXB2, HXB3, PV22)

CAS: 114991-28-5

Ref. 3D-FH108439

1mg
186.00 €
2mg
321.00 €
5mg
535.00 €
10mg
867.00 €
25mg
1,774.00 €
Estimated delivery in United States, on Thursday 23 May 2024

Product Information

Name:
HIV-1 env Protein gp120 (278-292) (strains BH10, BH8, HXB2, HXB3, PV22)
Synonyms:
  • H-Arg-Ile-Gln-Arg-Gly-Pro-Gly-Arg-Ala-Phe-Val-Thr-Ile-Gly-Lys-OH H-RIQRGPGRAFVTIGK-OH
  • H-Arg-Ile-Gln-Arg-Gly-Pro-Gly-Arg-Ala-Phe-Val-Thr-Ile-Gly-Lys-OH
Description:

The HIV-1 envelope protein, gp120, is a transmembrane glycoprotein that plays a key role in the viral entry process. The gp120 protein contains the binding site for the CD4 receptor and can be cleaved by proteases to remove the membrane-spanning domain. The resulting soluble gp120 (sgp120) is an important co-receptor for HIV infection of target cells such as prostate cancer cells. The sgp120 binds to heparin sulfate proteoglycans on the surface of target cells and triggers cellular activation pathways including angiogenic factors, which induce cell proliferation and migration. This process is important for tumour growth and metastasis, inflammatory bowel disease, and other inflammatory diseases. The sgp120 has also been shown to activate pro-apoptotic proteins such as Bcl-2 family members and Bax. These proteins play a crucial role in apoptosis pathway by regulating mitochondrial membrane integrity, cytochrome c release from mitochond

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
1,655.95 g/mol
Formula:
C73H126N26O18
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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