8-Hydroxyquinoline-5-sulfonic acid

CAS: 84-88-8

Ref. 3D-FH40559

Product Information

• Name: 8-Hydroxyquinoline-5-sulfonic acid
• Synonyms: 4(5)-Imidazolecarboxaldehyde Hydrochloride, 4-Hydroxyquinoline-5-Sulphonic Acid, 5-Quinolinesulfonic acid, 8-hydroxy-, 5-Sulfo-8-hydroxyquinoline, 5-Sulfo-8-quinolinol, 5-Sulfooxine, 8-Hydroxy-5-Quinolinesulfonic Acid, 8-Hydroxy-5-sulfoquinoline, 8-Hydroxylquinoline-5-sulfonic acid, 8-Hydroxyquinolin-5-Sulfonic Acid, 8-Oxyquinoline-5-sulfonic acid, 8-Quinolinol-5-Sulfonic Acid, 8-Quinolinone-5-Sulfonic Acid, NSC 105877, NSC 13139, NSC 220049, Oxine-5-sulfonic acid, Sulfoxine

Description

8-Hydroxyquinoline-5-sulfonic acid (8HQSA) is a fluorescence sensor that can be used as a fluorescent probe for the detection of DNA replication inhibitors. It has shown to have anti-cancer properties in vitro and in vivo. 8HQSA is a stable complex with metal ions, such as copper or zinc, and is biocompatible with living cells. This compound has been shown to selectively bind to DNA replication enzymes, such as k562 cells and bacterial dna gyrase, by electrochemical impedance spectroscopy. 8HQSA inhibits cellular growth through the inhibition of DNA replication and protein synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 225.22 g/mol
• Formula: C₉H₇NO₄S
• Purity: Min. 95%