6-Methoxyindole-2-carboxylic acid methyl ester

CAS: 98081-83-5

Ref. 3D-FM08190

Product Information

• Name: 6-Methoxyindole-2-carboxylic acid methyl ester
• Synonyms: Methyl 6-methoxy-2-indolecarboxylate2-Methoxycarbonyl-6-methoxyindole, methyl 6-methoxy-1H-indole-2-carboxylate
• CAS: 98081-83-5

Description

6-Methoxyindole-2-carboxylic acid methyl ester is a pyrroloquinoline alkaloid with cytotoxic and antiproliferative activities. It inhibits the growth of cancer cells in culture by inducing apoptosis and cell cycle arrest. 6-Methoxyindole-2-carboxylic acid methyl ester has been shown to be effective against breast cancer cell lines in vitro and to inhibit the proliferation of breast cancer cells in vivo. This compound also inhibits the growth of a number of other cancer cell lines such as prostate, colon, lung, liver, stomach, and leukemia. The mechanism of action for this compound is thought to be due to its ability to act as an intramolecular quencher of reactive oxygen species (ROS) or as an inhibitor of DNA synthesis through inhibition of ribonucleotide reductase activity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 205.21 g/mol
• Formula: C₁₁H₁₁NO₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C11H11NO3/c1-14-8-4-3-7-5-10(11(13)15-2)12-9(7)6-8/h3-6,12H,1-2H3
• InChI key: InChIKey=OPUUCOLVBDQWEY-UHFFFAOYSA-N
• SMILES: COC(=O)c1cc2ccc(OC)cc2[nH]1