DL-α-Methyltryptophan

CAS: 153-91-3

Ref. 3D-FM48617

Product Information

• Name: DL-α-Methyltryptophan
• Synonyms: α-Me-DL-Trp-OH, Alpha-Methyl-DL-Tryptophan, H-.alpha.-Me-DL-Trp-OH, A-Methyl-L-Tryptophan
• CAS: 153-91-3

Description

DL-alpha-Methyltryptophan is a metabolite of the amino acid tryptophan. It is a monoamine neurotransmitter that has been implicated in brain function and inflammatory lesions. DL-alpha-Methyltryptophan can be used as a potential drug target for the treatment of Parkinson's disease, depression, and anxiety disorders. The hydroxyl group on the indole ring of DL-alpha-Methyltryptophan gives it an increased reactivity with oxygen, which allows it to be oxidized by monoamine oxidase B (MAO B) to 3-hydroxyanthranilic acid. This reaction can be inhibited by MAO A inhibitors such as clorgyline or selegiline. The oxidation of DL-alpha-Methyltryptophan leads to increased concentrations of serotonin in the brain and increased activity of aminotransferases.

• Brand: Biosynth

Chemical properties

• Molecular weight: 218.25 g/mol
• Formula: C₁₂H₁₄N₂O₂
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C12H14N2O2/c1-12(13,11(15)16)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,14H,6,13H2,1H3,(H,15,16)
• InChI key: InChIKey=ZTTWHZHBPDYSQB-UHFFFAOYSA-N
• SMILES: CC(N)(Cc1c[nH]c2ccccc12)C(=O)O